Name : Hamid Reza
Family : Haghighatkhah
Resident : Masoome Raoufi
Gender : Male
Age : 50
Head & Neck Imaging
50 Y/O man,altered mental status.
Imaging Procedures and Findings
MR demonstrates abnormal high signal on T2WI and low signal on T1, corresponding to the regions of central pontine demyelination. Additionally, extrapontine site of involvement has seen in white matter of thalamus.CT scan show central pontin radioluency.
Central pontine myelinolysis (CPM) is a disorder that results in characteristic demyelination of the central pons. This is most commonly seen in patients with electrolyte abnormalities, particularly involving hyponatremia.Occasionally, cases have been associated with diabetes, leukemia, transplant recipients, chronically debilitated patients, and others with conditions resulting in chronic malnutrition. MR characteristically demonstrates abnormal high signal on T2WI, corresponding to the regions of central pontine demyelination .Additionally, extrapontine sites of involvement have been described in this condition, including the white matter of the cerebellum, thalamus, globus pallidus, putamen, and lateral geniculate body, giving rise to the term extrapontine myelinolysis
Central pontine myelinolysis (CPM)
Brant WE, Helms CA. Fundamentals of Diagnostic Radiology, 3rd edition. P196-198.